Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study

Not yet recruiting

• Conditions: Induction of Labor Affected Fetus / Newborn; Pregnancy Late

• Registration Number: NCT06184139
• Lead Sponsor: University of Palermo

Brief Summary

To evaluate the effect of maternal age and body mass index (BMI) on oral misoprostol induction of labor for late-term pregnancies.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-11-18
• Status Verified: 2023-12
• Study Start: 2023-12
• Study First Submitted QC: 2023-12-14
• Last Update Submitted: 2023-12-14
• Study First Posted: 2023-12-28
• Last Update Posted: 2023-12-28
• Primary Completion: 2024-01
• Study Completion: 2024-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 104

Inclusion Criteria

• Late term pregnancies out of labor,
• Bishop score < 7

Exclusion Criteria

• labor (defined as presence of at least three painful uterine contractions every ten minutes),
• uterine tachysystole (>5 contractions within 10 minutes for two consecutive 10-minute periods),
• hypertonic uterus,
• abnormal CTG,
• contraindications to vaginal delivery (fetal malpresentation such as breech presentation or transverse situation, fetal macrosomia, abnormally implanted placenta, active genital herpes infection, cervical cancer),
• patients with parity > 4,
• medical contraindication to misoprostol (asthma, glaucoma),
• women with previous hysterotomies.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Safety and tolerability of misoprostol for induction of labor	290 days of pregnancy	Efficacy induction of labor for late term pregnancies according to age and BMI

Trial Locations

Locations (1)

Andrea Etrusco; 🇮🇹 Palermo, Italy