Pilot study to distinguish between intracerebral hemorrhage and ischemic stroke using a non-invasive acustoscerebrography in combination with established serum biomarkers.
- Conditions
- I63I61Cerebral infarctionIntracerebral haemorrhage
- Registration Number
- DRKS00021724
- Lead Sponsor
- ZNN, Klinik für Neurologie Universitätsklinikum Frankfurt a.M.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
(1) age = 18 years
(2) Relevant neurological deficit, National Institute of Health Stroke Scale (NIHSS) =6
(3) Admission to hospital within 6 hours of symptom onset.
(4) Evidence of an occlusion of the M1- or M2-artery on computed tomography (CT)-angiography or evidence of intracerebral hemorrhage in a supratentorial location
Exclusion Criteria
(1) Prior history of stroke (TIA, ischemia, hemorrhage) within the last months.
(2) Known history of brain Tumor
(3) Traumatic brain injury within the last 3 months (including head impact at symptom onset)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Description of a specific pattern of multispectral ultrasound distinguishing patients with ischemic from hemorrhagic strokes.
- Secondary Outcome Measures
Name Time Method (1) GFAP Serum Level (including a comparison of diagnostic accuracy with the ultrasound results)<br>(2) Volumetry of intracerebral hemorrhage according to the axbxc^2-method<br>(3) Severity of the clinical neurological deficit on hospital admission according to the National Institute of Health Stroke Scale <br>(4) Time between symptom onset and collection of blood sample <br>