CTRI/2023/07/054734尚未招募Unknown
To compare the serum level of Ipratropium Bromide delivered through pMDI versus nebulization during NIV therapy in acute exacerbation of COPD cases.
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Patients aged >40 years.
- •2.Clinically suspected patients in AECOPD.
- •3.Patients of COPD in type 2 respiratory failure and pH between 7.25-7.35.
排除标准
- •1.Any obstructive or restrictive respiratory disease other than COPD.
- •2.Hemodynamically unstable, defined as systolic blood pressure <90 mm Hg or mean arterial blood pressure <65 mm Hg despite appropriate volume resuscitation.
- •3.Patients in need of emergency intubation.
- •4.Arterial pH <7.25 or the pO2 below 45 mmHg despite oxygen therapy.
- •5.Patients in altered sensorium or Glasgow Coma Scale (GCS) less than 12.
- •6.Patients with facial deformity, trauma or surgery where proper oronasal mask seal cannot be ensured.
- •7.Patients with hypersensitivity to Levosalbutamol, coronary artery disease (CAD), tachyarrhythmias, and diabetic ketoacidosis (DKA).
研究者
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