Modified Guarnieri-Desarda Technique Versus Lichtenstein Technique in Inguinal Hernia Repair

Not Applicable

Recruiting

• Conditions: Inguinal Hernia
• Interventions: Procedure: Lichtenstein Mesh-Based Hernioplasty; Procedure: Combined Modified Guarnieri-Desarda Tissue-Based Hernioplasty

• Registration Number: NCT06595628
• Lead Sponsor: Cairo University

Brief Summary

The aim of this study is to compare the surgical outcome of both Lichnichtien tension free mesh hernioplasty of inguinal hernia and the combined modified Guarnieri Desarda technique in terms of postoperative pain, post operative complications (seroma, hematoma, wound infection), chronic inguinodenia, early recurrence and assessment of testicular vascularity and size by application of a testicular duplex and ultrasound.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-09-10
• Study First Submitted QC: 2024-09-12
• Study First Posted: 2024-09-19
• Study Start: 2024-10-10
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-12
• Last Update Posted: 2025-03-14
• Primary Completion: 2025-10-01
• Study Completion: 2025-10-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

• Adult male patients aged 18 years or older.
• Patients diagnosed with non-complicated inguinal hernia (both direct and indirect).
• Patients able to provide written informed consent to participate in the study.

Exclusion Criteria

• Patients younger than 18 years old.
• Patients with complicated hernias (e.g., inflamed, obstructed, or strangulated hernias).
• Patients with a recurrent inguinal hernia.
• Patients with weak or thin external oblique aponeurosis (intraoperative findings).
• Patients with a history of prior surgery in the inguinal region.
• Patients who refuse to participate in the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lichtenstein Mesh-Based Repair	Lichtenstein Mesh-Based Hernioplasty	Participants in this arm will undergo the Lichtenstein tension-free hernioplasty, which involves reinforcing the inguinal canal floor using a synthetic mesh. The mesh is fixed to the inguinal ligament and internal oblique aponeurosis, minimizing tension in the repair and reducing the risk of recurrence.
Combined Modified Guarnieri-Desarda Tissue-Based Repair	Combined Modified Guarnieri-Desarda Tissue-Based Hernioplasty	Participants in this arm will receive the combined modified Guarnieri-Desarda tissue-based repair. This approach involves reconstructing the inguinal canal without the use of synthetic mesh, using the patient's own tissues to reinforce the canal and reduce tension. The technique combines aspects of both the Guarnieri and Desarda methods, aiming to preserve the natural physiology of the inguinal canal while providing tension-free repair.

Primary Outcome Measures

Name	Time	Method
Postoperative Pain Assessment	At 2 weeks, 1 month, 3 months, and 6 months post-surgery.	Postoperative pain will be evaluated using the Mankoski Pain Scale (0-10). Pain scores will be recorded at different time intervals to assess immediate and long-term postoperative pain, with scores from 0 to 2 considered negligible, and scores from 3 to 10 considered significant.

Secondary Outcome Measures

Name	Time	Method
Incidence of Postoperative Complications	At 2 weeks, 1 month, and 3 months post-surgery.	The occurrence of postoperative complications such as seroma, hematoma, wound infection, and testicular complications (e.g., hydrocele, cord induration) will be recorded and analyzed for each group.
Hernia Recurrence Rate	At 6 months and 1 year post-surgery.	The rate of hernia recurrence will be assessed through clinical examination and imaging, comparing recurrence between the Lichtenstein mesh-based repair group and the modified Guarnieri-Desarda tissue-based repair group.
Testicular Vascularity	At 3 months post-surgery.	Testicular vascularity will be evaluated using testicular duplex and ultrasound, comparing any changes pre- and post-surgery between the two groups.

Trial Locations

Locations (1)

Kasralainy; 🇪🇬 Cairo, Egypt