NCT07196280已完成不适用
Protective Effect of 5-Alpha Reductase Inhibitors on Atherosclerotic Cardiovascular Disease in Populations With BPH: Evidence From UK Biobank Cohort and Chinese Single Center Database Studies
Chinese PLA General Hospital0 个研究点目标入组 10,000 人开始时间: 2012年1月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10,000
- 主要终点
- Atherosclerotic Cardiovascular Disease
研究概览
简要总结
To assess the impact of 5-alpha reductase inhibitors (5-ARIs) on the incidence of atherosclerotic cardiovascular disease (ASCVD) in patients with benign prostatic hyperplasia (BPH).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed with BPH or users of 5-ARIs
排除标准
- •individuals who had cancer prior to the start of follow-up and those with pre-existing ASCVD
结局指标
主要结局
Atherosclerotic Cardiovascular Disease
时间窗: Started taking 5α-reductase inhibitors until December 1, 2022
While both CVD and ASCVD are composite disease categories, CVD encompasses a broader range of cardiovascular and cerebrovascular conditions. To ensure homogeneity in disease classification, we focused on ASCVD, which primarily refers to atherosclerosis-related cardiovascular and cerebrovascular diseases, including ischemic heart disease (IHD) and cerebrovascular disease (CeVD)
次要结局
未报告次要终点
研究者
Qing Yuan
Professor
Chinese PLA General Hospital
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