跳至主要内容
临床试验/NCT02821091
NCT02821091终止不适用

Biomechanics Research in the Effects of Interactive Dynamic Balance Training on Postural and Gait Control in Older Adults

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2015年4月16日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
终止
入组人数
27
试验地点
1
主要终点
Timed Up and Go Test

研究概览

简要总结

Aim 1: Determine the relationships between muscle quality and balance performance as well as any association with fracture and fall history in older adults.

Muscle quality will be calculated from the information of muscle strength and body composition (strength/lean muscle mass). The investigators will compute the joint torque during functional activates using biomechanical data from the 3-D motion analysis, whereas the lean skeletal muscle mass will be determined by the bioelectrical impedance analysis (BIA). Clinical and functional assessments for balance performance will also be conducted. Fracture and fall history prior to the testing will be recorded retrospectively.

Aim 2: Identify the relationships between force usages during balance perturbation in older adults.

Lateral and forward/backward perturbation while walking will be used to elicit balance recovery responses. The degree of necessary joint force and how this relates to a person's functional capacity at specific joint levels will be determined by the torque demand to capacity ratio (DCR: task demands relative to strength capacity). The DCR provides a joint-specific unified scalar quantity representing the balance recovery demand normalized by the maximum muscle strength capacity of an individual. It would indicate whether a person can recover balance and to what extent of his/her maximum capacity is taxed.

Aim 3: Examine the effectiveness and long-term effects of a novel 2-month personalized strengthening and balance training program on improving balance performance in older adults.

Personalized strengthening and balance training exercise will be personalized based on the results of biomechanical assessments, using the Modular Interactive Tiles System (MITS) and split-belt balance perturbation instrumented treadmill. The exercise group will receive training 2 times a week for 2 months and the age-matched control group will maintain their usual daily life activities. All assessments will be performed at baseline, and 1 week after training. Follow-up telephone interviews will be conducted at 6, 9, and 12 months following the training period.

详细描述

Aging populations has become a global issue. Fall is a prevalent concern among aging adults that can cause fracture, injury or mortality. Identifying the factors related to falls occurring within this aging population is essential for the development of effective regimes for fall prevention. Studies have shown that muscle quality and good posture alignments are critical for balance control in older adults. Older adults often combining with muscles weakness (sarcopenia), bone loss (osteoporosis) and lead to increased spine kyphosis causing vertebral fractures and poor balance control. Therefore, the long-term objectives of this work are to prevent fall in older adults by improving the function of degenerative muscles. The proposed research can provide needed information regarding the processes of balance control in this aging population, and can potentially be applied to individuals with poor balance who at high risk of fall. Three specific aims for this 3 years research project are described as follow:

Aim 1: Determine the relationships between muscle quality and balance performance as well as any association with fracture and fall history in older adults.

Muscle quality will be calculated from the information of muscle strength and body composition (strength/lean muscle mass). The investigators will compute the joint torque during functional activates using biomechanical data from the 3-D motion analysis, whereas the lean skeletal muscle mass will be determined by the bioelectrical impedance analysis (BIA). Clinical and functional assessments for balance performance will also be conducted. Fracture and fall history prior to the testing will be recorded retrospectively.

Aim 2: Identify the relationships between force usages during balance perturbation in older adults.

Lateral and forward/backward perturbation while walking will be used to elicit balance recovery responses. The degree of necessary joint force and how this relates to a person's functional capacity at specific joint levels will be determined by the torque demand to capacity ratio (DCR: task demands relative to strength capacity). The DCR provides a joint-specific unified scalar quantity representing the balance recovery demand normalized by the maximum muscle strength capacity of an individual. It would indicate whether a person can recover balance and to what extent of his/her maximum capacity is taxed.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •For control young adults group:
  • •able to stand and walk for 5 minutes independently without assistant
  • •aging between 20 and 59 years old
  • •For older adults group:
  • •able to stand and walk for 5 minutes independently without assistant
  • •aging between 60 and 80 years old;

排除标准

  • •pre-existing major lower-extremity pathology (e.g., Chronic ankle instability or severe osteoarthritis)
  • •neurological disorders or balance difficulties (e.g., Vertigo, poor vision, dizziness, stroke, or epilepsy) that would prevent standing for the duration of the testing procedures without the aid of an assistive device
  • •health conditions (e.g., Heart disease, uncontrolled hypertension, chronic obstructive pulmonary diseases) that would exclude participation in a balance exercise program.

研究组 & 干预措施

Exercise old adults

Experimental

Healthy adults, age between 60 to 80 yeas old received interactive dynamic balance training

干预措施: Interactive Dynamic Balance Training (Other)

Control young adults

No Intervention

Healthy adults, age between 20 to 59 yeas old

Control old adults

No Intervention

Healthy adults, age between 60 to 80 yeas old

结局指标

主要结局

Timed Up and Go Test

时间窗: Up to 52 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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