MedPath

Effectiveness and Safety of Firmagon®

Completed
Conditions
Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma
Interventions
Other: Firmagon given by prescription according to SPC
Registration Number
NCT00930319
Lead Sponsor
Ferring Pharmaceuticals
Brief Summary

Effectiveness and Safety of Firmagon® in Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma. The period until Prostate Specific Antigen (PSA) progression during the Firmagon® therapy is to be documented and related to the testosterone values measured in the course of therapy (if available). Other clinical parameters, the patients' quality of life and the direct and indirect costs incurred by the medical care for the advanced hormone-dependent prostate carcinoma and its consequences will be evaluated. In this context the medical outcome and the life quality are defined as effectiveness and benefit value parameters. Both the effectiveness under daily life circumstances and economic variables of the therapy can thus be shown and compared within an analysis of costs vs. benefits or costs vs. effectiveness.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
676
Inclusion Criteria
  • therapeutic need according to SPC
  • written informed consent
Exclusion Criteria
  • contraindications according to SPC

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
1Firmagon given by prescription according to SPCPatients with Advanced Hormone-dependent Prostate Carcinoma treated with Firmagon according to SPC
Primary Outcome Measures
NameTimeMethod
duration of the PSA progression-free survivalopen (until therapy end or stop)
Secondary Outcome Measures
NameTimeMethod
3. quality of lifeopen (until therapy end or stop)
2. number of ADRs and SUSARsopen (until therapy end or stop)
1. testosterone levelsopen (until therapy end or stop)

Trial Locations

Locations (88)

Investigational Site, Hohenzollerndamm 47a

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Berlin, Germany

Investigational Site, Albert-Einstein-Straße 2

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Berlin, Germany

Investigational Site, Reilstraße 129 a

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Halle, Germany

Investigational Site, Alte Holstenstraße 16

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Hamburg, Germany

Investigational Site, Heinrich-Rieger-Str. 15

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Aalen, Germany

Investigational Site, Mehrower Allee 22

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Berlin, Germany

Investigational Site, Helenenstraße 10-12

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Gotha, Germany

Investigational Site, Am Museumsturm 4

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Nordhorn, Germany

Investigational Site, Treppenstraße 3

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Bielefeld, Germany

Investigational Site, Steinweg 27

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Halle (Saale), Germany

Investigational Site, Zeppelinstraße 1

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Köln, Germany

Investigational Site, Custodistraße 3-17

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Köln, Germany

Investigational Site, Hohenzollernring 70

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Münster, Germany

Investigational Site, Am Stadtpark 2

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Nürnberg, Germany

Investigational Site, Moosbürger Str. 13

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Weiden, Germany

Investigational Site, Lustgartenstraße 3

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Spremberg, Germany

Investigational Site, Kopernikusplatz 7

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Nürnberg, Germany

Investigational Site, Hirschstraße 22

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Ulm, Germany

Investigational Site, Postgasse 1

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Weiden, Germany

Investigational Site, Friederikenstraße 30

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Köthen, Germany

Investigational Site, Osnabrücker Straße 1

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Nordhorn, Germany

Investigational Site, Hefnersplatz 1

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Nürnberg, Germany

Investigational Site, Niemeyerstraße 23

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Halle, Germany

Investigational Site, Im Steinbügel 13

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Frankfurt, Germany

Investigational Site, Siebenbrünnenpromenade 6-7

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Köthen, Germany

Investigational Site, Kaiserstraße 7

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Rastatt, Germany

Investigational Site, Seckenheimer Hauptstraße 107

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Mannheim, Germany

Investigational Site, N7, 9

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Mannheim, Germany

Investigational Site, Fürstenbergstraße 5

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Münster, Germany

Investigational Site, Carl-von-Ossietzky-Str. 151

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Chemnitz, Germany

Investigational Site, Prüner Gang 15

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Kiel, Germany

Investigational Site, Schulstraße 7

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Kiel, Germany

Investigational Site, Eppenreuther Straße 28

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Hof, Germany

Investigational Site, Johannisstraße 43

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Bielefeld, Germany

Investigational Site, Friedrich-Verleger Straße 5

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Bielefeld, Germany

Investigational Site, Postplatz 2

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Crailsheim, Germany

Investigational Site, Arminstraße 24

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Gelsenkirchen, Germany

Investigational Site, Nobelstraße 51

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Rostock, Germany

Investigational Site, Mainzer Straße 105

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Saarbrücken, Germany

Investigational Site, Olgastraße 139

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Ulm, Germany

Investigational Site, Kreuzstraße 3-5

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Duisburg, Germany

Investigational Site, Geschwister-Scholl-Str. 6

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Erfurt, Germany

Investigational Site, Markt 11

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Kiel, Germany

Investigational Site, Wilhelm-Ewald-Weg 1

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Köln, Germany

Investigational Site, Grüner-Turm-Straße 7-9

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Ravensburg, Germany

Investigational Site, Bahnhofstraße 17

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Nordhausen, Germany

Investigational Site, Viktoriastraße 2

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Saarbrücken, Germany

Investigational Site, Bahnhofstraße 8

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Nordhausen, Germany

Investigational Site, Hindenburgstraße 10 A

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Rastatt, Germany

Investigational Site, Heinrich-Nordhoff-Straße 49

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Wolfsburg, Germany

Investigational Site, Gartenstraße 22

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Ravensburg, Germany

Investigational Site, Große Wasserstraße 2 - 3

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Rostock, Germany

Investigational Site, Kirchplatz 6a

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Spremberg, Germany

Investigational Site, Olgastraße 103

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Ulm, Germany

Investigational Site, Trelleborger Straße 10B

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Rostock, Germany

Investigational Site, Porschestraße 100

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Wolfsburg, Germany

Investigational Site, Rudolff-Seifert-Straße 11

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Berlin, Germany

Investigational Site, Weidenfelder Straße 1

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Aalen, Germany

Investigational Site

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Überlingen, Germany

Investigational Site, Endresstraße 12

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Ansbach, Germany

Investigational Site, Platenstraße 15

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Ansbach, Germany

Investigational Site, Allee der Kosmonauten 47

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Berlin, Germany

Investigational Site, Frölichstraße 13

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Augsburg, Germany

Investigational Site, Prinzregentenstraße 4

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Augsburg, Germany

Investigational Site, Lipschitzallee 20

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Berlin, Germany

Investigational Site, Pasteurstraße 8

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Berlin, Germany

Investigational Site, Elbeallee 83

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Bielefeld, Germany

Investigational Site, Wisbyer Straße 16

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Berlin, Germany

Investigational Site, Zeppelinring 7

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Biberach, Germany

Investigational Site, Trierer Straße 70 - 72

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Bonn, Germany

Investigational Site, St. Augustiner-Straße 21

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Bonn, Germany

Investigational Site, Dr.-Franz-Mertens-Straße 8

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Bremerhaven, Germany

Investigational Site, Georgstraße 44

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Bremerhaven, Germany

Investigational Site, Flemmingstraße 1b

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Chemnitz, Germany

Investigational Site, Clausstraße 44

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Chemnitz, Germany

Investigational Site, Unritzstraße 21 c

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Chemnitz, Germany

Investigational Site, Karlstraße 30

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Crailsheim, Germany

Investigational Site, Königstraße 49

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Duisburg, Germany

Investigational Site, Juri-Gagarin-Ring 94

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Erfurt, Germany

Investigational Site, Eschersheimer Landstr. 544

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Frankfurt, Germany

Investigational Site, Schützenberg 10

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Gotha, Germany

Investigational Site, Feldmarkstraße 109

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Gelsenkirchen, Germany

Investigational Site, Zum Ehrenmal 21

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Gelsenkirchen, Germany

Investigational Site, Fuhlsbüttler Straße 182

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Hamburg, Germany

Investigational Site, Herthastraße 12

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Hamburg, Germany

Investigational Site, Grindelberg 3

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Hamburg, Germany

Investigational Site, Tangstedter Landstraße 77

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Hamburg, Germany

Investigational Site, Enoch-Widmann-Straße 5

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Hof, Germany

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