Efficacy Of Oral Minoxidil Versus Topical Minoxidil in Androgenetic Alopcecia : A Randomised Control Trial
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Oral minoxidil plus platelet rich plasma is considered superior to topical minoxidil plus platelet rich plasma for the treatment in terms of increase in hair density of males with androgenetic alopecia.
研究概览
简要总结
All consenting male patients fulfiling the inclusion and exclusion criteria will be divided into 2 groups . group A - will recieve oral minoxidil 2.5mg once daily for 3 months along with platelet rich plasma and group B will recieve topical minoxidil twice daily 5% lotion plus platelet rich plasma for 3 months.
total 3 sittings of platelet rich plsama will be planned for each group at monthly intervals.
outcome assesment will be done on the basis of increase in hair density in terms of terminal and vellous hair in each treatment group at baseline , 4 , 8 12 weeks. along with patient satisfaction and dermatology life quality index at the baseline and 3 months later.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Male
入选标准
- •All consenting male patients aged 18-45 yrs.
- •All new clinically diagnosed cases with androgenetic alopecia of grade: III-VI according to Hamilton and Norwood classification.
排除标准
- •1.Patients with a history of Autoimmune disease and Severe systemic illness (such as uncontrolled DM or hypertension, liver or renal diseases, cardiovascular problems) 2.Any patients with known sleeping disorders.
- •3.Immunocompromised patients.
- •4.Patient with unrealistic expectations.
- •5.Alopecia caused by other factors such as telogen effluvium, alopecia areata, or scarring alopecia.
- •6.Patients who are positive for HIV/ HBsAg /HCV/ VDRL.
结局指标
主要结局
Oral minoxidil plus platelet rich plasma is considered superior to topical minoxidil plus platelet rich plasma for the treatment in terms of increase in hair density of males with androgenetic alopecia.
时间窗: 3 months
次要结局
- 1.Patient Satisfaction score(2.Dermatology life quality index)
研究者
Dr Paridhi Vaidh
KALINGA INSTITUTE OF MEDICAL SCIENCES