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Clinical Trials/NCT05705934
NCT05705934
Not yet recruiting
Not Applicable

Investigation of The Effects of Holistic Group Exercise Program on Muscle Thickness and Physical Performance in Older Adults With Sarcopenia

Ondokuz Mayıs University0 sites34 target enrollmentMarch 30, 2023
ConditionsSarcopenia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcopenia
Sponsor
Ondokuz Mayıs University
Enrollment
34
Primary Endpoint
The Timed Up&Go Test
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

A decrease in muscle mass and function can cause the development of many chronic diseases, including sarcopenia. It has been reported that the best intervention for sarcopenia is exercise. Despite this, the optimal type of exercise for sarcopenia has not yet been determined. Although the holistic approach is used in the literature in the elderly population, it is noticeable that it does not find much space for itself in this patient group. In this study, it was aimed to examine the effects of holistic approach-based exercise program on individuals with sarcopenia.

Registry
clinicaltrials.gov
Start Date
March 30, 2023
End Date
November 30, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Ondokuz Mayıs University
Responsible Party
Principal Investigator
Principal Investigator

Kübra Tuz

Lecturer

Ondokuz Mayıs University

Eligibility Criteria

Inclusion Criteria

  • Being over the age of 65
  • Getting a diagnosis of sarcopenia
  • To be able to walk at least 10 meters independently in public
  • Getting a score of 4 and above from the clock drawing test
  • Volunteer individuals

Exclusion Criteria

  • Having a neurological disease
  • Having an uncontrollable cardiopulmonary disease
  • Acute illness that will prevent him/her from understanding and performing the exercises to be performed status or the presence of significant cognitive impairment
  • Providing continuity for less than 80% of the exercise program

Outcomes

Primary Outcomes

The Timed Up&Go Test

Time Frame: Change from baseline at 12 weeks

It is a balance test used in the evaluation of functional mobility in the elderly. In the timed up and go (TUG) test, subjects are asked to rise from a standard armchair, walk to a marker 3 m away, turn, walk back, and sit down again. The elapsed time in this sequence is recorded in seconds. Patients wear their regular footwear and can use a walking aid, if needed.

Short Physical Performance Battery (SPPB)

Time Frame: Change from baseline at 12 weeks

The short physical performance battery (SPPB) is a group of measures that combines the results of the gait speed, chair stand and balance tests. It has been used as a predictive tool for possible disability and can aid in the monitoring of function in older people. The scores range from 0 (worst performance) to 12 (best performance). A patient's score below 10 is the inclusion criterion for sarcopenia.

Muscle Mass

Time Frame: Change from baseline at 12 weeks

Muscle ultrasound (US) is a feasible and practical tool to predict sarcopenia. It provides scope for the efficient assessment of muscle quality whilst providing insight into the pathophysiology of sarcopenia in addition to the diagnosis of low muscle mass. US has distinct advantages over other available modalities for muscle mass because the tool allows for separate measurements of individual muscle groups in addition to being safe and portable.

Secondary Outcomes

  • SARC-F Questionnaire(Change from baseline at 12 weeks)
  • 30-Second Chair Stand Test(Change from baseline at 12 weeks)
  • Depression(Change from baseline at 12 weeks)
  • Hand Grip Strength(Change from baseline at 12 weeks)
  • Charlson Comorbidity Index(Change from baseline at 12 weeks)
  • Berg Balance Test(Change from baseline at 12 weeks)
  • Mini Nutritional Assessment (MNA)(Change from baseline at 12 weeks)

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