Biomarkers for fatigue in patients with Myasthenia Gravis
Recruiting
- Conditions
- cognitieve vermoeidheidMyasthenia Gravis10029317
- Registration Number
- NL-OMON55325
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 115
Inclusion Criteria
myasthenia gravis with anti-acetyl choline receptor antibodies
Exclusion Criteria
- A medical history of other active auto-immune disorders for which the patient
currently receives a medical treatment, such as thyroid disease or rheumatoid
arthritis.
- A recent medical history of neoplasms.
- Substance abuse.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is a serum biomarker which correlates with levels of<br /><br>fatigue. We expect this biomarkers to be (partly) influenced by disease<br /><br>severity and treatment. Therefore this study has the option to include a<br /><br>longitudinal design (part II) with data and samples over the course of 6-12<br /><br>months (2 visits). During this part II of the study fluctuations in fatigue<br /><br>will be related to fluctuations in the previously identified biomarkers.</p><br>
- Secondary Outcome Measures
Name Time Method <p>We will collect information on depression scores, age, sex, BMI, medication and<br /><br>degree of physical activity as these factors are associated with fatigue and<br /><br>are likely to influence results. </p><br>