Effects of Daily Supplementation of 5-HTP on Body Composition, a Randomized Investigation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 65
- 试验地点
- 2
- 主要终点
- Body Composition
研究概览
简要总结
The purpose of this investigation was to compare supplementation with 5-HTP to placebo on indices of body composition. A randomized trial compared a sample of 48 resistance-trained individuals taking either 100 mg of 5-hydroxytryptophan supplementation or a placebo.
The investigators tested anthropometric measurements using a multi-frequency bioelectrical impedance device (InBody® 270). The primary outcome (i.e., changes in anthropometric measurements) was assessed at the first visit (pre-test-) and post-test (8 weeks). Secondary outcomes include resting heart rate, blood pressure, and dietary intake.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
盲法说明
All subjects and investigators were blinded.
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy or free of disease
- •Minimum of 1 year of regular physical activity. Regular physical activity is defined by a minimum of 150 minutes of aerobic activity or performing muscle-strengthening exercises at least 2 days a week.
排除标准
- •Physically inactive
- •Regularly used sleep aids of any kind
- •Currently taking selective serotonin reuptake inhibitors (SSRIs) and/or 5-HTP containing supplements.
研究组 & 干预措施
Control
The placebo consisted of maltodextrin. Subjects were instructed to consume one capsule daily at their convenience for 8 weeks.
干预措施: Placebo (Other)
结局指标
主要结局
Body Composition
时间窗: 8 weeks
The percentage of fat, bone, and muscle was assessed pre and post visit using multi-frequency bioelectrical impedance device (InBody® 270).
次要结局
- Blood Pressure(8 weeks)
- Resting Heart Rate(8 weeks)
- Dietary Habits(8 weeks)
研究者
Cassandra Evans
Co-principal Investigator
Nova Southeastern University