A method for non-invasive intracranial pressure measurement in glaucoma
Completed
- Conditions
- GlaucomaPOAG10018307
- Registration Number
- NL-OMON45351
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
50-70 years of age
Presence of DPOAEs in one ear
For healthy controls: Upright IOP of 21mmHg or lower
For high pressure glaucoma: Diagnosed Glaucoma, upright IOP over 21mmHg before the onset of IOP lowering treatment, and established disease progression rate based on perimetry
For normal tension glaucoma: Diagnosed Glaucoma, upright IOP of 21mmHg or lower with or without IOP lowering treatment, and established disease progression rate based on perimetry
For high IOP with no glaucoma: Upright IOP of 22mmHg or higher
Written informed consent.
Exclusion Criteria
No presence of DPOAEs
For healthy controls, any eye disease or family history of glaucoma
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Amplitudes and phase angles of DPOAEs as a function of posture for different<br /><br>subgroups of Glaucoma and healthy controls. Blood pressure, corneal thickness,<br /><br>and systemic medication will be recorded as well, being possible confounders.</p><br>
- Secondary Outcome Measures
Name Time Method <p>N/A</p><br>