Het effect van een DPP-4 remmer op de reactie van het lichaam bij een hypoglykemie bij patiënten met type 1 diabetes.
Completed
- Conditions
- EN - NLType 1 diabetes mellitus - type 1 diabetes mellitusHypoglycaemia - hypoglykemieGlucagon - glucagon
- Registration Number
- NL-OMON25642
- Lead Sponsor
- Academic Medical Center, Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
1. Male;
2. Age 18-40 years;
Exclusion Criteria
1. Impaired awareness of hypoglycaemia;
2. BMI > 27 kg/m2;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glucagon response to insulin induced hypoglycaemia measured as AUC (area under the curve).
- Secondary Outcome Measures
Name Time Method 1. Other counterregulatory hormone responses to insulin induced hypoglycaemia measured as AUC;<br /><br>2. Symptomatic hormone responses to insulin induced hypoglycaemia.