Strength Training on Pancreatic Cancer
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 6
- 主要终点
- muscle mass and strength
研究概览
简要总结
The purpose of this study is to determine whether prednisone, methotrexate, and cyclophosphamide are effective in the treatment of rapidly progressive hearing loss in both ears due to autoimmune inner ear disease (AIED).
详细描述
Sudden out-of-hospital cardiac arrest (OOH-CA) remains a significant cause of death, in spite of recent declines in overall mortality from cardiovascular disease. Existing methods of emergency resuscitation are inadequate due to time delays inherent in the transport of a trained responder with defibrillation capabilities to the side of the OOH-CA victim. Existing Emergency Medical Services (EMS) systems typically combine paramedic Emergency Medical Technician (EMT) services with some level of community involvement, such as bystander cardiopulmonary resuscitation (CPR) training. Some communities include automated external defibrillators (AEDs) at isolated sites or in mobile police or fire vehicles. A comprehensive, integrated community approach to treatment with AEDs would have community units served by these volunteer non-medical responders who can quickly identify and treat a patient with OOH-CA. Such an approach is termed Public Access Defibrillation (PAD).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with pancreatic carcinomas after surgery (resection or exploration)
- •given consent
排除标准
- •acute infection
- •no mobility or ability for walking or standing
- •severe neurological disorders (apoplex, morbus Parkinson, paresis of the lower extremeties)
- •severe cardiac or cardiovascular diseases (z.B. heart insufficiency NYHA III, myocardial infarction <3 months)
- •rhytmical disorders, that contraindicate ergospirometric examinations
- •cardiac therapy with digitalis pharmacy
- •unclear syncopes
- •severe pulmonal insufficiency
- •renal insufficiency (GFR < 30% at Krea >3 mg/dl)
- •synchronous participation in an other clinical trial
结局指标
主要结局
muscle mass and strength
时间窗: after 8 weeks of intervention
次要结局
- quality of life(after 8 weeks of intervention)
