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临床试验/NCT02202460
NCT02202460Unknown不适用

The Potential Biomark of Serious Psychosis: Including the Variation of Brain MRI, BDNF and Oxidative Stress-related Immunological Factors in Different Phases.

Central South University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2014年8月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
200
试验地点
1
主要终点
Oxidative Stress-related Immunological Factors

研究概览

简要总结

Patients suffer from Serious Psychosis may have variation in immunological factors,BDNF and MRI.

详细描述

Patients suffer from Schizophrenia and Mood Disorders may have variation in immunological factors(TNF-α,IL-2,IL-6,IL-10,etc),BDNF and Brain MRI.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis with Schizophrenia , Bipolar Disorder or Major Depression by DSM-5

排除标准

  • Unstable physical conditions

结局指标

主要结局

Oxidative Stress-related Immunological Factors

时间窗: 18 month

Blood test will be conducted every 3 month to assess the concentration of oxidative stress-related immunological factors including TNFα,TGFβ, MCP-1,IL-1α,IL-2,IL-6,IL-10,IL-12.

次要结局

  • BDNF(18 month)

研究者

发起方
Central South University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Renrong Wu

Professor

Central South University

研究点 (1)

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