Primary Lesion Treatment for Bone Metastases
Not Applicable
Not yet recruiting
- Conditions
- Bone Metastases
- Interventions
- Procedure: palliative surgeryRadiation: radiotherapy
- Registration Number
- NCT05665790
- Lead Sponsor
- Shanghai 6th People's Hospital
- Brief Summary
This study will carry out a prospective cohort study to study the effect of different primary leison treatment modes on disease control, quality of life, economic cost and survival period of patients with bone metastases from breast cancer and lung cancer by giving radiotherapy or palliative surgery or not giving local treatment for the primary lesion in patients with bone metastases from breast cancer or lung cancer
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
- HR positive breast cancer patients with bone metastasis or Non-small-cell lung cancer patients with bone metastasis；
- Aged over 18;
- ECOG：0-1；
- Patients who benefit clinically(CR+PR) after 6 months of treatment.
Exclusion Criteria
- The expected life span is less than 3 months;
- Have serious cardiovascular and cerebrovascular diseases, blood coagulation dysfunction, and cannot tolerate surgery;
- Allergies to narcotic drugs;
- The patient refused the treatment decision of the integrated team.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description palliative surgery palliative surgery - radiotherapy radiotherapy -
- Primary Outcome Measures
Name Time Method Disease control rate at 1 year 1 year Disease control rate
- Secondary Outcome Measures
Name Time Method Progression-Free Survival 1 year Overall Survival 1 year