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临床试验/NCT06060639
NCT06060639招募中不适用

Variation of Echocardiographic Parameters After Red Blood Cell Transfusion in Emergency Department Anemic Patients

Centre Hospitalier Universitaire de Nīmes2 个研究点 分布在 1 个国家目标入组 116 人开始时间: 2023年11月9日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
116
试验地点
2
主要终点
E/A ratio modification

研究概览

简要总结

The goal of this interventional study is to asses echocardiographic variations in emergency department's elderly patients receiving red blood cell transfusion. The main questions it aims to answer are :

  • is there a modification of echocardiographic parameters after red blood cell transfusion ?
  • which parameter is the most impacted by red blood cell transfusion ? Participants will have a transthoracic echocardiography before, just after and 15 minutes after red blood cell transfusion.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patient needing red blood cell transfusion
  • social protection

排除标准

  • fluid filing over 500 mL of crystalloids
  • transfusion in the last hour

结局指标

主要结局

E/A ratio modification

时间窗: Base line, just after and 15 minutes after red blood cell transfusion

E/A ratio permits to estimate left ventricle pressure

次要结局

  • New York Heart Association scale (NYHA) modification(baseline and 24 hour after red blood cells transfusion)
  • E wave deceleration time(Base line, just after and 15 minutes after red blood cell transfusion)
  • E/e' ratio modification(Base line, just after and 15 minutes after red blood cell transfusion)
  • Lung score modification(Base line, just after and 15 minutes after red blood cell transfusion)
  • Velocity-time Integral (VTI) modification(Base line, just after and 15 minutes after red blood cell transfusion)

研究者

发起方
Centre Hospitalier Universitaire de Nīmes
申办方类型
Other
责任方
Sponsor

研究点 (2)

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