KCT0002823
Recruiting
未知
Investigation of the brain pathophysiology of addiction disorder using cerebral glucose metabolism and brain network analysis and evaluation of the treatment effect of neuromodulation
The Catholic University of Korea, Incheon St. Mary's Hospital0 sites80 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- The Catholic University of Korea, Incheon St. Mary's Hospital
- Enrollment
- 80
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\[Alcohol use disorder group]
- •(a) Diagnosed with alcohol use disorder based on the Diagnostic and Statistical Manual of Mental Disorders\-5 and taking standard medication, and alcohol abstinence status will be considered.
- •(b) Adult men and women aged 20 to 60 years
- •\[Problematic drinking group]
- •(a) More than 4 standard drinks (SD) for one occasion or more than 14 SD for one week (men) / More than 3 SD for one occasion or more than 7 SD for one week (women) or scores of 8 or more on Alcohol Use Disorders Identification Test (AUDIT) for men / scores of 6 of more on AUDIT for women
- •(b) Adult men and women aged 20 to 60 years
- •\[Normal control group]
- •(a) Adult men and women aged 20 to 60 years
Exclusion Criteria
- •Exclusion criteria
- •(a) Have major medical, neurological, or psychiatric illnesses
- •(b) Pregnant, lactation, or have a pregnancy plan
- •(c) Not compatible for MRI and PET\-CT (internal metal and medical devices, claustrophobia, etc.)
- •(d) History of seizures
- •(e) Problems with stimulation electrodes due to deformity of the scalp, inflammation reaction or other dermatological problems
- •(f) History of cancer in the past three years
- •(g) Surgery for brain vessels such as brain surgery or carotid surgery
- •(h) Dyspnea when sitting still
- •(i) Loss of consciousness for more than one hour due to other causes other than general anesthesia
Outcomes
Primary Outcomes
Not specified
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