Evaluation of Post-Post-Endoscopic Retrograde Cholangiopancreaticography Pain (ERCP) as a Predictor for Post-ERCP Pancreatitis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Post-ERCP Acute Pancreatitis
- Sponsor
- Nicola Frei
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Association between Pain 1 hour after ERCP
- Last Updated
- 4 years ago
Overview
Brief Summary
Pancreatitis is the most common complication after ERCP, although its frequency varies significantly depending on the study from < 2% up to 40%.
Based upon data from studies that have included unselected patients, post-ercp pancreatitis (PEP) is mild, moderate, and severe in 45%, 44%, and 11% of cases, respectively. Dysfunction of the sphincter Oddi, female gender, younger age, previous history of pancreatitis, prolonged procedure time and pancreatic guidewire passages are well-known independent risk factors for PEP.
This study will assess whether the development of PEP can be predicted by Visual analogue scale (VAS) level 1 hour after ERCP.
Investigators
Nicola Frei
MD
Cantonal Hospital of St. Gallen
Eligibility Criteria
Inclusion Criteria
- •Age \>18 years
- •Scheduled for ERCP for any reason
Exclusion Criteria
- •Absence of consent
- •Language barrier
- •No endoscopic advance to the papilla vateri
- •Active pancreatitis at the time of the procedure
- •Mental disability
Outcomes
Primary Outcomes
Association between Pain 1 hour after ERCP
Time Frame: 1 hour
Secondary Outcomes
- Predictive value of VAS for PEP Predictive value of VAS for PEP(1 hour)
- Association between VAS level and severity of PEP(1 hour)