Treatment of schizophrenia with antipsychotic drugs
Phase 2
- Conditions
- Schizopherenia.Schizophrenia
- Registration Number
- IRCT138706051100N1
- Lead Sponsor
- Deputy of Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
the criteria of DSM-IV for schizopherenia; neuroleptic drug-naive or drug-free for at least 4 weeks; age range from 18-58 years; filling consent form; no drug tranqulization for at least five half life of the drug; no psychoactive drug therapy for at least 5 half life of the drug. Exclusion criteria: Accompanied disorders of axis 1 or 2 based on DSM-IV; evidence of neurological disease; History of any drug abuse; elevating hepatic enzymes; pregnancy; thyroid dysfunction; consumption of drugs interferring with HT25 or D2 receptors.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Alteration in cerebral perfusion. Timepoint: one month after using the drug. Method of measurement: cerebral perfusion scan.
- Secondary Outcome Measures
Name Time Method Changes in severity of clinical symptoms. Timepoint: one month after onset of the treatment. Method of measurement: PANSS and CGI tests for clinical symptom score.