KCT0007196
Recruiting
未知
Effect of blood pressure variability and nocturnal hypertension on hypertension-mediated organ damage and cardiovascular disease in elderly patients with hypertension
ConditionsDiseases of the circulatory system
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the circulatory system
- Sponsor
- Chungbuk National University Hospital
- Enrollment
- 1300
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients aged 65 or older with hypertension and enrolled in the target blood pressure study (HOWOLD\-BP trial, 2018\-09\-015\) among elderly hypertension subjects who voluntarily participated in this clinical trial and agreed to participate in the study.
Exclusion Criteria
- •It is the same as the exclusion criteria of the study on prognosis analysis according to target blood pressure when treating hypertension in elderly hypertension subjects (HOWOLD\-BP trial, 2018\-09\-015\). Patients who meet any of the following criteria cannot participate in this clinical trial.
- •1\) Subjects with all suspected history of secondary hypertension, such as aortic stenosis, hyperaldosterone, renal stenosis, cushing disease, chromium\-friendly cytoma, and polycystic nephrotic disease, and all suspected of secondary hypertension.
- •2\) Resistant hypertension subjects whose blood pressure is controlled to less than 140/90 mmHg using three or more antithrombotic drugs, including diuretics, or four or more antithrombotic drugs including diuretics, with blood pressure controlled to less than 140/90 mmHg.
- •3\) Subjects with orthostatic hypotension (One minute standing SBP \< 110 mmHg) accompanied by symptoms at the time of screening
- •4\) Subject to uncontrolled diabetes whose HbA1C value is defined to be 10% or higher at the time of screening.
- •5\) Subject to chronic kidney disease with maintenance dialysis or estimated GFR 1515 mL/min/1\.73 m2
- •6\) Subjects who have undergone acute coronary syndrome, heart surgery, and urgent percutaneous coronary intervention (PCI) within the last 3 months.
- •7\) Subject to systolic heart failure with a left ventricular uvula rate of less than 40% in the past history.
- •8\) Subjects with hypertrophic obstructive cardiomyopathy, aortic stenosis, severe valve disease, and hemodynamically significant congenital heart disease.
- •9\) Subject to acute stroke diagnosed with stroke within the last 3 months.
Outcomes
Primary Outcomes
Not specified
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