Indoor Air Quality Monitoring and Impact on Children's Health

Not Applicable

Recruiting

• Conditions: Cognition
• Interventions: Device: OurAir SQ 1750 - Mobile Air Purification System for indoor; Device: Sham intervention

• Registration Number: NCT06197477
• Lead Sponsor: Hasselt University

Brief Summary

This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe

Detailed Description

The LEARN project, funded by the European Commission, aims to gain an in-depth understanding about indoor air quality in schools and its impact on children's cognitive development. This involves evaluating school cohorts in three different countries (Belgium, Greece and Denmark). In participating schools, we measure and characterise indoor and outdoor air pollutants and evaluate the presence of exposure biomarkers and their effect on children's cognition. Measuring indoor air quality, exposure and creating remedial strategies are crucial steps to improve air quality in the school environment and ensure the well-being of children.

Study Timeline

• Study First Submitted: 2023-09-28
• Study Start: 2023-11-20
• Status Verified: 2024-01
• Study First Submitted QC: 2024-01-08
• Last Update Submitted: 2024-01-08
• Study First Posted: 2024-01-09
• Last Update Posted: 2024-01-09
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 900

Inclusion Criteria

• Boys and girls
• Attending school in the 4th -6th grade in elementary schools included in the study
• Signed informed consent form by legal representative

Exclusion Criteria

• Insufficient knowledge of local language (ie. Dutch, Greek, Danish) by child or parents

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Air purification	OurAir SQ 1750 - Mobile Air Purification System for indoor	The intervention will consist of air purification placed in the classrooms.
Control	Sham intervention	Filtration will be turned off in the air purifier placed in the classrooms in the control part of the study.

Primary Outcome Measures

Name	Time	Method
Change in the Memory Span Task score	at the end of the intervention and at the end of the sham intervention	Change in the number of longest list of items that a child can repeat back in correct order. Longer list of recalled items indicate better short term memory
Change in Correct Detection of continuous Performance Test	at the end of the intervention and at the end of the sham intervention	Change in the number of times the child responded correctly to the target alphanumeric stimulus. Higher rates of correct detections indicate better attentional capacity.
Change in the number of correct substitutions of Symbol Digit Modalities Test	at the end of the intervention and at the end of the sham intervention	Change in the the number of correct substitutions the child performed. Higher number of correct substitutions indicate better information processing ability.
Change in the Signal Detection Test score	at the end of the intervention and at the end of the sham intervention	Change in the number of correct detection of signals. Higher rates of correct detection indicate better perception ability

Trial Locations

Locations (1)

Hasselt University; 🇧🇪 Diepenbeek, Belgium