Development of Novel Assessments for Indoor Air Quality Monitoring and Impact on Children's Health - Cohorts in Schools & Biomarkers of Exposure
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 900
- 试验地点
- 2
- 主要终点
- Change in the Memory Span Task score
研究概览
简要总结
This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe
详细描述
The LEARN project, funded by the European Commission, aims to gain an in-depth understanding about indoor air quality in schools and its impact on children's cognitive development. This involves evaluating school cohorts in three different countries (Belgium, Greece and Denmark). In participating schools, we measure and characterise indoor and outdoor air pollutants and evaluate the presence of exposure biomarkers and their effect on children's cognition. Measuring indoor air quality, exposure and creating remedial strategies are crucial steps to improve air quality in the school environment and ensure the well-being of children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 9 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Boys and girls
- •Attending school in the 4th -6th grade in elementary schools included in the study
- •Signed informed consent form by legal representative
排除标准
- •Insufficient knowledge of local language (ie. Dutch, Greek, Danish) by child or parents
结局指标
主要结局
Change in the Memory Span Task score
时间窗: at the end of the intervention and at the end of the sham intervention
Change in the number of longest list of items that a child can repeat back in correct order. Longer list of recalled items indicate better short term memory
Change in Correct Detection of continuous Performance Test
时间窗: at the end of the intervention and at the end of the sham intervention
Change in the number of times the child responded correctly to the target alphanumeric stimulus. Higher rates of correct detections indicate better attentional capacity.
Change in the number of correct substitutions of Symbol Digit Modalities Test
时间窗: at the end of the intervention and at the end of the sham intervention
Change in the the number of correct substitutions the child performed. Higher number of correct substitutions indicate better information processing ability.
Change in the Signal Detection Test score
时间窗: at the end of the intervention and at the end of the sham intervention
Change in the number of correct detection of signals. Higher rates of correct detection indicate better perception ability
次要结局
未报告次要终点
研究者
Tim Nawrot
Professor
Hasselt University