Accuracy and Inter-observer Variability of Lung Ultrasound in COVID-19 Pneumonia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Accuracy of the diagnosis of interstitial syndrome by lung ultrasound
研究概览
简要总结
COVID-19 is a rapidly spreading and very contagious disease caused by a novel coronavirus that can lead to respiratory insufficiency. In many patients, the chest radiograph at first presentation be normal, and early low-dose CT-scan is advocated to diagnose viral pneumonia. Lung ultrasound (LUS) has similar diagnostic properties as CT for diagnosing pneumonia. However, it has the advantage that it can be performed at point-of-care, minimizing the need to transfer the patient, reducing the number of health care personnel and equipment that come in contact with the patient and thus potentially decrease the risk of spreading the infection.
This study has the objective to examine the accuracy of lung ultrasound in patients with proven COVID-19 pneumonia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •high probability CT thorax or chest X-ray for viral pneumonia within five days of the day of inclusion
- •positive COVID-19 nasopharyngeal swab within 10 days of inclusion
- •18 years or older
- •Oxygen saturation of < 93% in ambient air
- •Signed written informed consent
排除标准
- •Contra-indication for lung ultrasound
- •Other causes of hypoxia or of pulmonary infiltrates on CT thorax or chest X-ray
结局指标
主要结局
Accuracy of the diagnosis of interstitial syndrome by lung ultrasound
时间窗: within 2 weeks after first subject included
The diagnostic accuracy of lung ultrasound is more than 90% compared to low-dose CT or chest X-ray for the detection of viral pneumonia in patients with COVID-19 infection.
Inter-observer variability
时间窗: within 2 weeks after first subject included
The interobserver variability by lung ultrasound between the 2 observers for the diagnosis of interstitial syndrome by lung ultrasound is \> 0.6 measured by the Kappa score
次要结局
未报告次要终点
研究者
Prof. dr. Michiel Thomeer
Prof.Dr.Michiel Thomeer
Hasselt University