Effect of Preoperative Oral Carbohydrates on Quality of Recovery
- Conditions
- Evidence of Cholecystectomy
- Registration Number
- NCT02555020
- Lead Sponsor
- Yonsei University
- Brief Summary
Carbohydrate loading is an important component of enhanced recovery pathways. Preoperative carbohydrate treatments have been widely adopted as part of enhanced recovery after surgery (ERAS) or fast-track surgery protocols. Although fast-track surgery protocols have been widely investigated and have been shown to be associated with improved postoperative outcomes, some individual constituents of these protocols, including preoperative carbohydrate treatment, have not been subject to such robust analysis.To assess the effects of preoperative carbohydrate treatment, compared with placebo or preoperative fasting, on postoperative recovery and insulin resistance in adult patients undergoing elective surgery.
- Detailed Description
Patients received 400 mL of oral isotonic glucose (No NPO®, Daesang, Korea) 12 hours before anesthesia and 400 mL 2 hours before. CHL composition was standard: 12.5 g of carbohydrate per 100 mL, 12% monosaccharide, 12% disaccharide, 76% polysaccharide, 250 mOsm/kg and 50 kcal.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 153
- ASA (I/II)
- Laparoscopic cholecystectomy.
- KAROFSKY PERFORMANCE SCALE >70,
- No history of major operation
- DM patients
- GE reflux Hx patients.
- No- compliance,
- Previous Abdominal Surgery History
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Quality of Recovery score using the QoR-40 Questionnaire We check the QoR-40 at POD1 after cholecystectomy , an expected average 3days We check the QoR-40 Questionnaire at discharge day
- Secondary Outcome Measures
Name Time Method