Uterine Artery Color Doppler Parameters After Bilateral Uterine Artery Ligation for Postpartum Hemorrhage
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postpartum Hemorrhage
- Sponsor
- Tanta University
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Color Doppler parameters
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The aim of this study is to assess Uterine artery color doppler parameters after bilateral uterine artery ligation (BUAL) for Postpartum Hemorrhage.
Detailed Description
Obstetric haemorrhage is the main reason of maternal death in both countries with high and poor incomes. Most of these deaths occurred within the first 24 hours following birth. Placenta accrete, retained placenta, genital tract lacerations, uterine rupture, and coagulation abnormalities are established risk factors for postpartum hemorrhage. The management of Idiopathic pulmonary hemosiderosis (IPH) and postpartum hemorrhage relies on numerous considerations: type of delivery (vaginal or caesarean delivery), bleeding etiology (uterine atony, trauma, retained placenta) and hemodynamic stability. In the first stage, early identification, and treatment with uterotonics, suturing the lacerations, and fundal massage are crucial. When bleeding persist, even in the aggressive medical treatment, suitable surgical intervention should be performed. Surgical therapy relies on the patient's desire to maintain fertility, the severity of the bleeding, and the surgeon's experience. Historically, peripartum hysterectomy was the only available management to prevent postpartum hemorrhage but, in some instances, hysterectomy alone is insufficient to control the bleeding. Also, the desire to preserve fertility have resulted in the development of other techniques, such as pelvic embolization and internal iliac artery ligation (IIAL)and bilateral uterine artery ligation (BUAL). Bilateral uterine artery ligation (BUAL) is the most popular surgical procedure for quick management of postpartum hemorrhage. It may be performed alone or with conjugation with other postpartum hemorrhage methods in with success rate exceeds 90 %. Recanalization is a natural process that may occur following vascular structure closure with a suture or radiological embolization.
Investigators
Ahmed Ossman
Assistant professor
Tanta University
Eligibility Criteria
Inclusion Criteria
- •70 women aged between 20 and 35 years old.
- •Undergoing Bilateral Uterine Artery Ligation after Postpartum Hemorrhageafter cesarean section
- •resistant to medical treatment, and did not need to hysterectomy.
Exclusion Criteria
- •Patients with male factor, tubal factor, and absence of lactation.
- •Diabetes mellitus, hypertension, morbid obesity, autoimmune disease, or vascular disease in the history, smoking.
- •Intrauterine growth restriction in previous pregnancies history, detection of a uterine anomaly or a medical condition, as well as administration of a hormonal treatment during the study.
- •Uncontrolled bleeding is needed for a hysterectomy.
Outcomes
Primary Outcomes
Color Doppler parameters
Time Frame: After Bilateral Uterine Artery Ligation
Color Doppler parameters for measuring the UtA diameters as UtA pulsatility Index will be recorded
Secondary Outcomes
- The uterine artery's descending branches(After Bilateral Uterine Artery Ligation)
- The uterine artery's ascending branch(After Bilateral Uterine Artery Ligation)
- Color Doppler parameters(After Bilateral Uterine Artery Ligation)