Comparison of the Effect of Using Photobiomodulation with Platelet-Rich Fibrin on Dental Sockets Healing

Phase 3

Conditions: Platelet-Rich Fibrin, Photobiomodulation.

Registration Number: IRCT20230222057497N1

Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 36

Inclusion Criteria

Patients over 18 Years of Age Referring to the Special Clinic of the Sari Dental Faculty who have Extensive Irreparable Caries, Failed Root Canal Therapy, Periodontal Disease, Tooth Fracture, Indications for Extraction of Anterior Teeth and Premolars (Maxilla and Mandible)
Intact Surrounding Alveolar Bone (Remaining Bone at least Two-Thirds of the Root Length)
Tooth Socket with Four Healthy Walls after Extraction
Patients Who Willing to Participate in the Study
Teeth that Do not Require Surgical Methods to Remove and Do not Require Using of Surgical Burs
Patients Who have the Ability to Participate in Examinations and Follow-up
ASA I-II Patinets

Exclusion Criteria

Patients with Poor Oral Hygiene
Pregnant or Lactating Women or Patients Who are Planning to Get Pregnant
Smokers (More than ten Cigarettes per Day) and Alcoholism
Patients with Uncontrolled Systemic Disease and History of Head and Neck Radiotherapy and Weak Immune System
Chronic Treatment with Any Drug that Affects Bone Function: Heparin, Cyclosporine, Bisphosphonate, Chemotherapy Drugs
Presence of Periapical or Periodontal Considerable Lesions around the Corresponding Teeth and Presence of Dehiscence and Fenestration in the Buccal Bone Plate
Contraindications for Tooth Extraction
Allergy to Any of the Study Products
A Severe Acute lnfection or Any Other Factor that Limits the Opening of the Mouth

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vertical height” and buccolingual” width of alveolar ridge, Soft tissue healing”, Keratinized gingival width”, Pain”, Bone density”. Timepoint: At the beginning of the study (before the start of the study) and 8 weeks after tooth extraction. Method of measurement: Periodontal Probe, Visual Analogue Scale, Cone Beam CT Scan, Inspection, Fractal Analysis.

Secondary Outcome Measures