Biomarkers in Idiopathic Juvenile Arthritis
- Conditions
- Idiopathic Juvenile Arthritis
- Interventions
- Other: blood sample for identifying biomarkers
- Registration Number
- NCT02343770
- Lead Sponsor
- University Hospital, Montpellier
- Brief Summary
Juvenile idiopathic arthritis (JIA) is the most common form of arthritis in children. The etiology is unknown. Several types of arthritis fall under the JIA heading. Oligoarticular JIA with antinuclear antibodies affects about half of all children. There 's no specific markers. Our purpose is to identify new markers in this pathology. The ProtoArray®Human Protein Microarray allows rapid and efficient detection of protein interaction using a suitable protein or small molecule probe. The investigators hope so detect novel potential autoantigen biomarkers specific in JIA.
- Detailed Description
We select 10 patients with inclusion criteria and 10 controls. We analyse their blood sample (5ml). The ProtoArray® Microarray allows to detect novel protein-protein interactions, to rapidly perform serum profiling using a sensitive method to detect potential autoantigen biomarkers. The ProtoArray® Human Protein Microarray is a high-density protein microarray containing thousands of purified human proteins for protein interaction screening.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description idiopathic juvenile arthritis blood sample for identifying biomarkers blood sample control blood sample for identifying biomarkers blood sample
- Primary Outcome Measures
Name Time Method identification of specific autoantigen biomarkers 1 day Identify blood sampling biomarkers of juvenile idiopathic arthritis
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Cardiology paediatric consultation, Arnaud de Villeneuve Hospital
🇫🇷Montpellier, France