"Remind to Move" Treatment Versus Constraint-induced Movement Therapy for Children With Hemiplegic Cerebral Palsy: A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hemiplegic Cerebral Palsy
- Sponsor
- The Hong Kong Polytechnic University
- Enrollment
- 73
- Primary Endpoint
- Jebsen-Taylor Hand Function Test (JTHFT)
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The aim of this study was to determine the effects of an innovative child-friendly remind-to-move treatment (RTM) treatment by comparing it with constraint-induced movement therapy (CIMT) on upper extremity outcomes in children with hemiplegic Cerebral Palsy. In an evaluator-blinded randomized controlled trial, 73 children, among of whom 20 in Manual Ability Classification System level I, 38 level II, and 15 level III, were recruited from 3 special schools and randomized to receive 75-hour RTM (n=25) and CIMT (n=24) programme over 15-weekdays, and conventional treatment (n=24). The primary outcomes were Jebsen-Taylor Hand Function Test (JTHFT) and Bruininks-Oseretsky Test of Motor Proficiency (BOTMP-II) Subtest 3 for assessing the motor efficiency at baseline, posttest, and 1- and 3-month follow-up.
Investigators
Kenneth N. K. Fong
Associate Professor
The Hong Kong Polytechnic University
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of Hemiplegic Cerebral Palsy
- •Aged 5 to 16 years
- •Ability to follow instructions
- •Ability to grasp and release light objects, and at least 20° wrist and 10°fingers in metacarpophalangeal joints extension from full flexion for the affected hand
- •Manual Activity Classification System (MACS) 19 grades I, II or III of the affected hand
Exclusion Criteria
- •Severe cognitive, visual, or auditory disorder
- •Seizure and health problems not associated with cerebral palsy
- •Predominant spasticity or contracture grades more than 3 of Modified Ashworth Scale 20 on wrist and finger flexors, forearm pronators and ⁄ or thumb adductors
- •Receiving new pharmaceutical (i.e. botulinum toxin injections) and/or surgical interventions within 6-month before study
Outcomes
Primary Outcomes
Jebsen-Taylor Hand Function Test (JTHFT)
Time Frame: Change from Baseline at 3 weeks (plus follow up at 1 month and 3 months after training)
Bruininks-Oseretsky Test of Motor Proficiency (2nd ed.) (BOTMP-II)
Time Frame: Change from Baseline at 3 weeks (plus follow up at 1 month and 3 months after training)
Secondary Outcomes
- Caregiver Functional Use Survey (CFUS)(Change from Baseline at 3 weeks (plus follow up at 1 month and 3 months after training))
- Ratio of movement duration on the affected hand from accelerometer(Change from Baseline at 3 weeks (plus follow up at 1 month and 3 months after training))
- Active range of motion (AROM) as measured by digital goniometer(Change from Baseline at 3 weeks (plus follow up at 1 month and 3 months after training))
- Power grip strength as measured by dynamometer(Change from Baseline at 3 weeks (plus follow up at 1 month and 3 months after training))