Effect of the Visual Information Change in Functional Dystonia

Not Applicable

Terminated

• Conditions: Torticollis; Movement Disorders; Neurologic Manifestations; Central Nervous System Diseases; Dyskinesias; Dystonia; Nervous System Diseases; Dystonic Disorders
• Interventions: Device: prism glasses

• Registration Number: NCT03270189
• Lead Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary

Cervical dystonia occurring only during the writing task is a rare form for which there is no established treatment. Many authors agree that alteration of sensory integration is associated with dystonia. Similar disturbances in the integration of oculomotor information could have a role in cervical dystonia forms involving visuo-cervico-manual coordination such as handwriting. We hypothesize that orthoptic treatment by wearing prisms when writing (i) will reduce the abnormal posture of the head occurring whilst writing and remove the associated nuchal pain; (ii) the correction after a period of systematic wearing of the prisms during handwriting tasks will have a sustainable effect allowing to keep a normal head position after the suppression of the prisms.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-29
• Study First Submitted QC: 2017-08-31
• Study First Posted: 2017-09-01
• Study Start: 2017-09-18
• Primary Completion: 2021-12-19
• Study Completion: 2022-09-19
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-11
• Last Update Posted: 2023-02-14

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Case

• Presenting a cervical dystonia that occurs only during handwriting tasks, diagnosed by a neurologist specialised in movement disorders
• Being treated or not by injection of Botulinum Neurotoxin (but last injection > 3 months before the initial assessment)

Control

• No cervical dystonia
• Same sex, age (± 5 years), socio-professional level and hand laterality as the cases

Exclusion Criteria

Case

• Cervical dystonia occuring in other circumstances than handwriting
• Neurological disease other than cervical dystonia (e.g. Parkinson's syndrome)
• Pain, trauma or pathology of the cervical spine of another cause than cervical dystonia and which have required medical or surgical treatment in the last 6 months preceding the initial assessment

Control

• Cervical disorders requiring medical or surgical treatment in the last 6 months prior to the tests
• Neurological disease affecting the cervical region or the writing hand
• Uncorrected visual disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
orthoptic treatment	prism glasses	Patients with cervical dystonia occuring only during handwriting.

Primary Outcome Measures

Name	Time	Method
measure of head movement occurring when writing	3 months	Difference of the angle measured with and without corrective prisms during the handwriting tasks

Trial Locations

Locations (1)

Fondation Ophtalmique Adolphe de Rothschild; 🇫🇷 Paris, France