Comparison of two type of steroidal eyedrops in treatment of uveitis
Phase 2
- Conditions
- acute anterior uveitis.Acute and subacute iridocyclitis
- Registration Number
- IRCT2012101511125N1
- Lead Sponsor
- Vice chancellor for research of Noor Ophthalmic research Center (NORC)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Eligibility criteria were:
1- age 16 years or older; 2- attack duration less than one week period; 3- no high intraocular pressure at presentation; 4-negative clues for infectious (e.g. corneal scars, iris atrophy) or granulomatous inflammation (e.g. granulomatous keratic precipitate or iris nodule).
The following exclusion criteria would be used:
1-eyes with hypopyon or florid fibrin formation; 2-prior unsuccessful topical treatment; 3- known cases of Behcet disease; 4-any slit-lamp evidence of significant blepharitis or meibomian gland dysfunction; 5-recent use of contact lenses.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anterior chamber inflammation. Timepoint: 1 week and 2 week after treatment. Method of measurement: Anterior chamber flare would be assessed using the laser flare photometer .anterior chamber cell would be assessed using slit lamp by standard grading system (1-4, SUN).
- Secondary Outcome Measures
Name Time Method Corneal toxicity. Timepoint: 1 week and 2 week after treatment. Method of measurement: Schirmer I test, tear break-up time, and corneal fluorescein staining scores.;Subjective discomfort. Timepoint: 1 week and 2 week after treatment. Method of measurement: Questionary.