Patients Prospectively Recruited in Knee and Hip Arthroplasty
Recruiting
- Conditions
- Hip / Knee Replacement Arthroplasty10005944
- Registration Number
- NL-OMON32983
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 3000
Inclusion Criteria
Participation in studies previously mentioned.
Exclusion Criteria
None.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Generic quality of life will be measured using the SF-36 and EQ-5D.<br /><br><br /><br>Illness-specific quality of life after hip replacement will be measured using<br /><br>the Oxford Hip Score (OHS) and the Hip disability and Osteoarthritis Outcome<br /><br>Score (HOOS).<br /><br>Illness-specific quality of life after knee replacement will be measured using<br /><br>the Oxford Knee Score (OKS) en de Knee injury and Osteoarthritis Outcome Score<br /><br>(KOOS).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Aseptic loosening will be determined by specific questions on readmissions and<br /><br>revision surgery, and a thorough review of the clinical charts.<br /><br><br /><br>DNS polymorphisms will be selected in relevant candidate genes for the immune<br /><br>system or osteoarthritis. Genetic association analyses will be performed in a<br /><br>case-control design.</p><br>