Ketamine effectiveness for acute agitatio

Phase 3

• Conditions: Acute agitation.; Restlessness and agitation; agitation

• Registration Number: IRCT20230612058465N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

All acutely agitated patients enrolled in the study. Treatable causes such as hypoxia and hypoglycemia were evaluated in if present, treated.

Exclusion Criteria

Any sensitivity to ketamine or haloperidol, past medical history of dissection or myocardial infarction, or QT prolongation lead to exclude from the study.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Agitation control based on RASS score. Timepoint: After admission, 30 and 60 minutes after the drug administration. Method of measurement: Agitation control will be assess by Richmond Agitation and Sedation Score.

Secondary Outcome Measures

Name	Time	Method
The sedation time based on minutes, the side effects of drugs include apnea, nausea and vomiting, need for intubation, tachycardia, hypertension, tachycardia, QT prolongation, tachycardia, and dysrhythmias. Timepoint: At admission and 30 and 60 minutes after drug administration. Method of measurement: Any side effects and time to sedation(minutes) will document.