Regulation of the Receptor of Advanced Glycation Endproducts in Sepsis after Polytraumatizatio

Recruiting

• Conditions: T07; A41.9; Unspecified multiple injuries; Sepsis, unspecified

• Registration Number: DRKS00000480
• Lead Sponsor: Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-07-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Polytraumatization with ISS>16

Exclusion Criteria

terminal kidney insufficiency, Diabetes mellitus, rheumathoid arthritis, Morbus Alzheimer, inflammatory bowel disease, artherisclerosis with previous myocardial ischemia, myocardial bypass surgery, stent implantation surgery

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of SIRS/sepsis (ACCP/SCCM consensus conference) during the initial 9 days after polytraumatization - aim is to examine the correlation between expression and abundance of the receptor on the cell membran and in the patients plasma with the development of a systemic inflammatory complication

Secondary Outcome Measures

Name	Time	Method
28-day-mortality