Effect of prebiotic fibres on Intestinal Health and Functioning - Prebiotics and metabolism

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 48 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•- Healthy, normal/overweight men and women (BMI * 20 kg/m2 <30kg/m2)
•- Aged 20-55 years
•- Caucasian
•- Normal fasting glucose (<6.1 mmol/L.)
•- Normal blood pressure (systolic blood pressure 100-140 mmHg, diastolic blood pressure 60-90 mmHg)
•- Weight stable in last 3 months (±2 kg)
•- A low defecation frequency, <4 times/week and no constipation or underlying pathology
•- A slow gastro-intestinal transit (> 50th percentile based on Sadik et al. 2003, 2004)

•- Woman lactating, pregnant or (post)-menopausal
•- Regular smokers
•- People with intensive fitness training, eg. athletes (*3 per week * 1 hour training)
•- Diabetes Mellitus (defined as FPG * 7.0 mmol/l and or 2h PG * 11.1 mmol/l)
•- Gastro-intestinal diseases or abdominal surgery, cardiovascular diseases, cancer, liver or kidney malfunctioning, disease with a life expectation shorter than 5 years.
•- Following a hypocaloric diet
•- Gluten intolerance
•- Regular use of laxation products, or use of antibiotics, probiotics or prebiotics 3 months prior to the start of the study
•- Current use of medication interfering with study intervention or interfering with study endpoints/hypotheses
•- Not to be able to understand the study information
•- Blood donation 2 months prior to the study and during the study
•- Participation in other studies

发起方

Medisch Universitair Ziekenhuis Maastricht