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临床试验/NCT04719754
NCT04719754Unknown不适用

Epidemiology and Clinico-investigative Study of Abnormal Vaginal Discharge During Pregnancy

Assiut University1 个研究点 分布在 1 个国家目标入组 164 人开始时间: 2021年6月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
164
试验地点
1
主要终点
The prevalence of microorganism in the vaginal discharge during pregnancy.

研究概览

简要总结

Vaginitis among women of childbearing age is well acknowledged as a public health concern due to its high occurrence. Vulvovaginitis is a disorder of the vulva and/or vagina caused by infection, inflammation, or changes in the flora.

There are many types of infections that affect the vagina, the most common three types of infection: bacterial vaginosis, trichomoniasis, and candidiasis. Bacterial vaginosis is the most common vaginal infection in women of reproductive age causing thin and milky vaginal discharge with a fishy odor. Trichomoniasis causes a frothy, greenish-yellow discharge with a foul smell.

Vaginal Candidiasis is one of the most common fungal infections of the female genital tract and the second most common vaginal infection affecting women of reproductive age (after the bacterial infection worldwide. It affects more than 75% of women at least once in their lifetime, with approximately 50% of them also suffering a single recurrence.

About 75% of patients suffering from candidiasis are asymptomatic, but it may be symptomatic with clinical picture characterized by itching, vaginal pain, vulvar burning sensation, dyspareunia, dysuria and mildly unpleasant odor, erythema and vulvar edema, white-yellowish plaques on the walls of the vagina and cervix and cheesy vaginal discharge. The risk of vulvo-vaginal candidiasis increases by 30% during pregnancy also in pregnancy, the presence of vaginitis is related to abortion, intrauterine infection, fetal growth retardation, premature rupture of membranes, preterm birth, low birth weight, puerperal infection, and other adverse pregnancy outcomes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
19 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • At any gestational age
  • Age of patient: 19-40

排除标准

  • Women in labor
  • Women with current vaginal bleeding
  • Women with current preterm rupture of membrane
  • Women immunocompromised women
  • Women patients who refused to participate in the study

结局指标

主要结局

The prevalence of microorganism in the vaginal discharge during pregnancy.

时间窗: 9 months

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Doaa Makarem Hassan

Resident

Assiut University

研究点 (1)

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