CTRI/2025/09/094168
Not yet recruiting
Phase 4
Outcome assessment of minimally invasive non-surgical therapy (MINST) in combination with emdogain versus guided tissue regeneration combination therapy for class II mandibular furcation defects. A randomized controlled trial
Dr Athul krishna P1 site in 1 country90 target enrollmentStarted: October 4, 2025Last updated:
Overview
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Dr Athul krishna P
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- To compare the post treatment (one year) clinical attachment level (CAL) in patients treated
Overview
Brief Summary
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 25.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Presence of Class II mandibular furcation defects.
- •(Hamp et al 1975) Systemically healthy Sound Endodontic status Adequate keratinized gingiva.
Exclusion Criteria
- •Pregnancy or lactation.
- •Uncontrolled diabetes Smokers History of allergy to any components of emdogain.
- •Use of medications affecting periodontal health (e.g., bisphosphonates).
- •Inability to undergo surgical procedures.
- •Recent antibiotic medication history Class III furcation defects (Hamp et al 1975) Patients unwilling to participate due to social/religious reasons for use of emdogain.
Outcomes
Primary Outcomes
To compare the post treatment (one year) clinical attachment level (CAL) in patients treated
Time Frame: 3rd month,6th month,one year
with Class II mandibular furcation defects with MINST combined with emdogain compared to
Time Frame: 3rd month,6th month,one year
GTR combination therapy
Time Frame: 3rd month,6th month,one year
Secondary Outcomes
- 1. To compare the Post treatment (one year) reduction in probing pocket depth (PPD),(gingival recession, horizontal clinical attachment level (HCAL) between Emdogain)
Investigators
Dr ATHUL KRISHNA P
GOVERNMENT DENTAL COLLEGE KOTTAYAM
Study Sites (1)
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