Effects of Montmorency Cherry Supplementation on Sleep and Inflammatory Outcomes

Michigan State University1 site in 1 country34 target enrollmentFebruary 18, 2023

Overview

This study will test the effects of Montmorency cherry supplementation on sleep outcomes and inflammatory biomarkers.

Registry

clinicaltrials.gov

Start Date

February 18, 2023

End Date

April 17, 2024

Last Updated

7 months ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Sponsor

Responsible Party

Principal Investigator

Robin Tucker

Associate Professor

Michigan State University

•body mass index (BMI) of ≥ 25.0 kg/m2;
•sleep issues as identified by a global score of 5 or greater on the Pittsburgh Sleep Quality Index (PSQI) and/or a score 8 or higher on the Insomnia Severity Index (ISI);
•ability to adhere to a diet low in antioxidants during the study period; and
•willingness to wear a Fitbit for the duration of the study and to wear the Zmachine on selected nights.

Change in insomnia symptoms

Time Frame: Through study completion, two weeks for each arm

Insomnia Severity Index scores, scores range from 0-28, higher scores indicate worse outcomes

Change in total sleep time

Time Frame: Through study completion, two weeks for each arm

sleep duration in hours and minutes

Change in sleep quality

Time Frame: Through study completion, two weeks for each arm

Pittsburgh Sleep Quality Index scores, scores range from 0-21, higher scores indicate worse outcomes

Change in Interleukin-8(Through study completion, two weeks for each arm)
Change in Interleukin-17(Through study completion, two weeks for each arm)
Change in Tumor necrosis factor-alpha(Through study completion, two weeks for each arm)
Change in Interleukin-6(Through study completion, two weeks for each arm)
Change in C-reactive protein(Through study completion, two weeks for each arm)
Change in Anthropometrics(Through study completion, two weeks for each arm)