Leveraging Real-Time Medication Use Monitoring to Improve Adherence in Adults With Glaucoma
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- University of Tennessee
- Enrollment
- 5
- Locations
- 8
- Primary Endpoint
- Adherence follow-up
Study Overview
Brief Summary
This study will evaluate the effectiveness of real-time data collected on patients taking topical medication to treat glaucoma. Patients will be randomized to two groups, the first of which will only use the study device to take their medication, while the second will use the study device and receive on-demand reminder messages, when necessary.
Detailed Description
Adherence to topical medications to treat glaucoma remains sub optimal; however, our understanding of this behavior remains limited due to biased measures of medication use. The Kali Drop device is a potential improvement in our ability to capture medication use in patients using dropper bottles by precisely capturing the amount dispensed in real-time. Moreover, such technology creates data that can be leveraged into driving behavior change using connected mobile technology in order to improve adherence and, ultimately, health outcomes. While evidence suggests that reminders may improve adherence to glaucoma medications, the power of doing so using real-time data has yet to be explored. This study will compare simple monitoring of patients to those who are being monitored and who receive reminder messages when the system determines one is necessary due to a missed dose.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Health Services Research
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •18 years of age and older
- •Glaucoma diagnosis
- •Prescription for a prostaglandin indicated for glaucoma
- •Nonadherent (MPR<80%) in the last 3 months according to pharmacy records
- •Owns and operates a mobile phone and willing to receive periodic reminder messages
Exclusion Criteria
- •Existing chronic eye condition in addition to glaucoma
- •Scheduled for eye surgery in the next 90 days
- •Prescription for a medication that will not fit in the device
- •Non-English speaking
Arms & Interventions
Monitoring only
Patients in this arm will be given a real-time medication use monitor to use in dispensing their topical glaucoma medication for 3 months
Intervention: Medication monitoring only (Behavioral)
Monitoring and reminder
Patients in this arm will be given a real-time medication use monitor to use in dispensing their topical glaucoma medication for 3 months and will receive an automated reminder (text or voice) when a missed dose is determined by the device's system
Intervention: Medication reminder (Behavioral)
Outcomes
Primary Outcomes
Adherence follow-up
Time Frame: From study endpoint through the subsequent 3 months
Changes and differences in adherence to glaucoma medication between groups after the intervention
Adherence
Time Frame: From study baseline through the 3 months of the intervention
Changes and differences in adherence to glaucoma medication between groups
Secondary Outcomes
- Medication self-efficacy using the 10-item Glaucoma Medication Adherence Self-Efficacy Scale(Change from baseline over the 3-month intervention)