Smoking Cessation Program in the Preadmission Clinic

Not Applicable

Completed

• Conditions: Smoking
• Interventions: Drug: Smoking cessation counselling group

• Registration Number: NCT01320462
• Lead Sponsor: University Health Network, Toronto

Brief Summary

Main Hypothesis: The multifaceted intervention (preoperative counseling, pharmacotherapy by varenicline and follow up by quit line) in the preoperative clinic is more effective than the simple preoperative smoking intervention (brief advice and provision of information about the quit lines ) in terms of short-term and long-term quit rates

Objectives: To evaluate the effectiveness and feasibility of a multifaceted intervention (preoperative counseling, pharmacotherapy by varenicline and follow up by the quit line) in the preoperative clinic to help surgical patients quit smoking perioperatively and for the long-term.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2011-03-21
• Study First Submitted QC: 2011-03-21
• Study First Posted: 2011-03-22
• Status Verified: 2016-06
• Primary Completion: 2017-04
• Study Completion: 2017-04
• Last Update Submitted: 2017-05-04
• Last Update Posted: 2017-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 296

Inclusion Criteria

• Patients who smoke more than 10 cigarettes per day for more than 1 year
• And had no period of smoking abstinence longer than 3 months in the past year.
• Patients who are scheduled to have any elective surgery next 7 to 60 days. Patients > 18 years of age

Exclusion Criteria

• Patients unwilling or unable to give informed consent
• Patients who are pregnant and breast feeding
• Patients with any psychiatric disorder
• Patients who used nicotine replacement / bupropion within previous 3 months
• Cardiovascular disease within the past 6 months
• Any serious or unstable disease within the past 6 months
• Drug or alcohol abuse within the past year.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Smoking cessation group	Smoking cessation counselling group	Counselling, Pharmacotherapy and Smokers Help Line

Primary Outcome Measures

Name	Time	Method
pre-surgery counseling for quit smoking	1 year after surgery	In order to determine the prevalence of abstinence in long-term follow up (4, 12, 24 and 52 weeks), patients will be asked the following questions: * Have you been abstinent from smoking for the past four weeks? (4-week abstinence); * Do you currently smoke cigarettes everyday? (point prevalence); * Have you been abstinent from smoking since the last time you quit smoking? (continuous abstinence)

Secondary Outcome Measures

Name	Time	Method
perioperative complications	3 months after surgery	Secondary outcome measures that will be studied are as follows: The changes in the number of cigarettes consumed per day or 'stage of change' at 4, 12, 24 and 52 weeks after the initial assigned target quit date. The incidence of perioperative complications (until 30 days after surgery) as well as medication-related adverse events (and serious adverse events) will also be recorded (only those who in the smoking-cessation program).

Trial Locations

Locations (2)

Mount Sinai Hospital, Department of Anesthesia; 🇨🇦 Toronto, Ontario, Canada

Toronto Western Hospital, Department of Aneshtesia; 🇨🇦 Toronto, Ontario, Canada