NCT01104883已完成4 期
The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee Arthroplasty
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Total morphine consumption
研究概览
简要总结
The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing morphine consumption and pain, and at the same time improving mobilisation after total knee arthroplasty.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Total Knee Arthroplasty in spinal anaesthesia
- •BMI 18-40
- •Written informed consent
排除标准
- •Can not cooperate to the exam
- •Do not speak or understand Danish
- •Drug allergy
- •Alcohol or drug abuse
- •Daily consumption of strong opioids
- •Unable to complete the Timed Up and Go test preoperatively
研究组 & 干预措施
Adductor-Canal-blockade with saline
Placebo Comparator
Adductor-Canal-blockade with isotonic saline
干预措施: Adductor-Canal-blockade with saline (Procedure)
Adductor-Canal-Blockade
Experimental
Adductor-Canal-Blockade with ropivacaine
干预措施: Adductor-Canal-Blockade (Procedure)
结局指标
主要结局
Total morphine consumption
时间窗: 0-24 hours postoperative
Total morphine consumption at the interval 0-24 hours postoperative.
次要结局
- Total morphine consumption(0-26 hours postoperative)
- Pain during rest(0-26 hours postoperative)
- Pain during 45 degrees active flexion of the knee(0-26 hours postoperative)
- A change in pain in the placebo group(24-26 hours postoperative)
- Postoperative nausea(0-26 hours postoperative)
- Zofran consumption(0-26 hours postoperative)
- Sedation(0-26 hours postoperative)
- Mobilisation(20-26 hours postoperative)
- Postoperative vomiting(0-26 hours postoperative)
研究者
研究点 (2)
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