Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography

Not Applicable

Completed

• Conditions: Pulmonary Arterial Hypertension

• Registration Number: NCT02028299
• Lead Sponsor: George Washington University

Brief Summary

An echocardiogram using Definity contrast can provide the same information as the standard right heart catheterization.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04
• Primary Completion: 2012-07
• Study Completion: 2012-07
• Status Verified: 2013-04
• Study First Submitted: 2013-08-20
• Study First Submitted QC: 2014-01-03
• Last Update Submitted: 2014-01-03
• Study First Posted: 2014-01-07
• Last Update Posted: 2014-01-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

• Adult patients scheduled to undergo right heart catheterization at the George Washington University Hospital

Exclusion Criteria

• Patients with known or suspected right-to-left bi-directional or transient right-to-left shunts or pulmonary arteriovenous malformations, previously documented moderate to severe tricuspid regurgitation or moderate to severe pulmonary regurgitation, evidence of right ventricular hypokinesis, or prior adverse reaction to Definity or hypersensitivity to perflutren

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Measure Pulmonary Vascular Resistance using 2D Doppler Echocardiogram w/Definity Solution	Two Years	Correlation coefficients between the technique above the the gold standard right heart catheterization measures of pulmonary vascular resistance.