MedPath

Safety and Efficacy of Urtica Dioica Cataplasm in the Management of Osgood-Schlatter Disease in Young Athletes

Not Applicable
Not yet recruiting
Conditions
Osgood-Schlatter Disease
Interventions
Other: Urtica dioica cataplasm
Other: Placebo
Behavioral: Resting conditions
Registration Number
NCT07096037
Lead Sponsor
Faculty of Medicine, Sousse
Brief Summary

The primary objective of this clinical trial is to evaluate the efficacy and safety of a topical Urtica dioica cataplasm in managing knee pain and functional limitations in athletic children diagnosed with Osgood-Schlatter Disease. Efficacy will be assessed through changes in knee pain using the Visual Analog Scale (VAS) and functional outcomes using the Knee Injury and Osteoarthritis Outcome Score (KOOS). Three groups will be tested:

* UDC Group: topical application of Urtica dioica cataplasm

* Standard Care Group: oral vitamin D supplementation and physical rest

* Placebo Group: topical application of a placebo cataplasm using Beta vulgaris subsp. cicla

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
Male
Target Recruitment
90
Inclusion Criteria
  • Healthy male children between 7 and 15 years of age
  • Active in regular sports practice (e.g., football)
  • Clinically confirmed diagnosis of OSD
Exclusion Criteria
  • Known allergy to Urtica dioica
  • Presence of dermatological conditions or lesions on the knees
  • Recent use of anti-inflammatory medications
  • History of immune or chronic inflammatory diseases
  • Diagnosis of any other bone disorder

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Urtica dioica cataplasmUrtica dioica cataplasmTopical application of Urtica dioica cataplasm
Standard Care GroupVitamin DOral vitamin D supplementation and physical rest
Standard Care GroupResting conditionsOral vitamin D supplementation and physical rest
PlaceboPlaceboTopical application of a placebo cataplasm
Primary Outcome Measures
NameTimeMethod
Pain intensityAt each clinical visit during the intervention period (three times a week during 6 weeks).

measured using the Visual Analog Scale (VAS), a 10-cm line anchored by "no pain" (0) and "worst imaginable pain" (10). VAS scores will be recorded at each clinical visit during the intervention period.

Secondary Outcome Measures
NameTimeMethod
Functional knee statusAssessments will be done at baseline and after 6 weeks.

assessed using the KOOS-Child questionnaire, covering five subscales (pain, symptoms, activities of daily living, sport/recreation function, and knee-related quality of life). Scores range from 0 (extreme dysfunction) to 100 (no symptoms).

Return to sport6 weeks

defined as the number of days post-treatment needed to resume regular athletic activity.

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.