Study for the association of OSAHS with vulnerable plaque in coronary heart disease

Phase 1

• Conditions: Coronary heart disease

• Registration Number: ITMCTR1900002546
• Lead Sponsor: Xinjiang Uygur Autonomous Region Chinese Medicine Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Aged 18 to 80 years;
2. Improve coronary angiography and OCT, and at least one vascular stenosis is greater than 50%;
3. Improve sleep breathing monitoring, and diagnosed as OSAHS.

Exclusion Criteria

1. Tracheal intubation and mechanical ventilation;
2. Previous or current use of continuous positive airway pressure (CPAP);
3. Chronic renal insufficiency [eGFR < 60ml/(min*1.73m2)];
4. Cardiogenic shock (systolic arterial pressure <90mmHg), congestive heart failure (NYHA or Killip >= 3);
5. Acute phase of myocardial infarction (within two weeks);
6. Previous coronary stenting or coronary artery bypass grafting;
7. Lesions or severe stenosis of blood vessel curvature and/or severe calcification and failure of the OCT catheter to pass through the lesion;
8. Chronic occlusive disease;
9. Pregnancy.

Study & Design

• Study Type: Basic Science
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Apnea Hyponea Index;