Assessing the Impact of Two Methods of Continuous Veno-venous Hemodiafiltration on Time Nursing Work in Intensive Care

Not Applicable

Withdrawn

• Conditions: Acute Renal Failure
• Interventions: Procedure: Continuous veno-venous haemodiafiltration

• Registration Number: NCT00993733
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

The prevalence of acute renal failure in intensive care is estimated at between 5 and 20% depending on diagnostic criteria retained. And half of patients require the use of hemodialysis. Continuous veno-venous hemodiafiltration (CVVHDF) is one of the hemodialysis technique widely used in intensive care unit.

The CVVHDF is performed at the bedside, by a mobile generator with a semi permeable membrane, a blood circuit, a dialysate circuit and a feedback circuit.

The implementation of a CVVHDF requires the use of large amounts of biological liquid essential to enable the purification of blood during its passage through the artificial kidney.

The objective of this study is to assess time nursing work and the costs of each method.

Detailed Description

The prevalence of acute renal failure in intensive care is estimated at between 5 and 20% depending on diagnostic criteria retained. And half of patients require the use of hemodialysis. Continuous veno-venous hemodiafiltration (CVVHDF) is one of the hemodialysis technique widely used in intensive care unit.

The CVVHDF is performed at the bedside, by a mobile generator with a semi permeable membrane, a blood circuit, a dialysate circuit and a feedback circuit.

The implementation of a CVVHDF requires the use of large amounts of biological liquid essential to enable the purification of blood during its passage through the artificial kidney. The biological fluid may be supplied to the generator of CVVHDF in 2 ways:

* The conventional method, the most used: the generator operates with pockets containing dialysis fluid, these pockets to be changed regularly by nurses

* The on-line method: the generator operates with a specific water system supplying the dialysis fluid available in every room of the unit The objective of this study is to assess time nursing work and the costs of each method.

For this, 15 patients will be included in this study. Each patient performs 12 hours of each method (conventional and online), whose order will be randomized.

Study Timeline

• Study First Submitted: 2009-10-09
• Study First Submitted QC: 2009-10-09
• Study First Posted: 2009-10-12
• Study Start: 2010-09
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2016-03
• Last Update Submitted: 2016-03-22
• Last Update Posted: 2016-03-23

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patient affiliated with or beneficiary of a social security category
• Patient with a renal failure requiring a CVVHDF for at least 2 cycles of 12 hours

Exclusion Criteria

• N/A

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CVVHDF on-line	Continuous veno-venous haemodiafiltration	CVVHDF using a central water treatment plant, providing dialysate directly to the patient. They will perform a continuous veno-venous haemodiafiltration.
classical CVVHDF	Continuous veno-venous haemodiafiltration	CVVHDF using a mobile generator with dialysate bags. They will perform a continuous veno-venous haemodiafiltration.

Primary Outcome Measures

Name	Time	Method
time of nursing work required to realised a CVVHDF as a conventional and on line methods modality of supply compared to a method on-line	Day 1	The end of the study for the patient corresponds to the end of CVVHDF conventional and on line.

Secondary Outcome Measures

Name	Time	Method
costs of CVVHDF performed using a conventional and on-line methods	Day 1	The end of the study for the patient corresponds to the end of CVVHDF conventional and on line.