Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications

Not Applicable

Completed

• Conditions: Postoperative Pulmonary Complications (PPCs)

• Registration Number: NCT06862076
• Lead Sponsor: Indonesia University

Brief Summary

The aim of this study is to compare the effect of lung function prehabilitation to postoperative pulmonary complications on patient undergoing upper abdominal surgery treated in intensive care unit.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-01
• Primary Completion: 2024-06-30
• Study Completion: 2024-11-12
• Status Verified: 2025-03
• Study First Submitted: 2025-03-01
• Study First Submitted QC: 2025-03-05
• Last Update Submitted: 2025-03-05
• Study First Posted: 2025-03-06
• Last Update Posted: 2025-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• adults 18 years or older
• scheduled for the upper abdominal surgery under general anesthesia with intraoperative mechanical ventilation
• possess adequate cognitive function to comprehend and follow instructions
• possess sufficient physical capacity to perform structured prehabilitation exercises
• express willingness to participate in the intervention program before surgery

Exclusion Criteria

• pregnancy
• pre-existing severe pulmonary diseases such as chronic obstructive pulmonary disease (COPD)
• planned laparoscopic procedures
• history of significant neuromuscular impairment (e.g: stroke)
• declined to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Postoperative pulmonary complications	Postoperative day 1 and 3	Including pulmonary infections, atelectasis, and diaphragmatic dysfunction. Pulmonary infection is assessed using the Clinical Pulmonary Infection Score (CPIS) and with a threshold of \>6, atelectasis using Lung Ultrasound Score (LUS) of ≥1, and diaphragm ultrasound were used to evaluate diaphragm ratio. CPIS and LUS score assessments were conducted on postoperative day 1 and 3 by trained investigators, diaphragm ratio assessment was conducted preoperatively and on postoperative day 1 and 3, all findings were systematically recorded.

Trial Locations

Locations (1)

RSUPN dr. Cipto Mangunkusumo; 🇮🇩 Jakarta Pusat, Jakarta, Indonesia