Diabetes Nutrition Algorithms - Sugars: Galactose- and Fiber-induced Metabolic Improvement in the Dietetic Treatment of Type 2 Diabetes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Type 2 Diabetes
- Sponsor
- German Institute of Human Nutrition
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- metabolic improvement of type 2 diabetes
- Last Updated
- 5 years ago
Overview
Brief Summary
In animal models and retrospective studies, certain food components such as sugars and fiber have been detected as potential agents to influence development and progress of type 2 diabetes.
The DiNA study prospectively investigates, if non-soluble non-fermentable fibers (vs. soluble ones) and galactose (vs. palatinose) are capable to improvement metabolic parameters in patients with long-term type 2 diabetes and intensive insulin treatment.
Investigators
Prof. Dr. med. Andreas F. H. Pfeiffer
Director of the Department for Clinical Nutrition
German Institute of Human Nutrition
Eligibility Criteria
Inclusion Criteria
- •type 2 diabetes, insulin-dependent
- •high insulin resistance
Exclusion Criteria
- •accompanying disease, medication or metabolic disorder, which interact with glucose metabolism or eating behavior (e.g. renal insufficiency, major cardial insuffiency, untreated hypothyreosis, corticoid treatment, depression and other psychiatric disorders...)
Outcomes
Primary Outcomes
metabolic improvement of type 2 diabetes
Time Frame: 4 weeks
metabolic improvement of type 2 diabetes, as to be shown via hyperinsulinemic-euglycaemic clamp, mixed-meal test and daily demand of insulin units