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Effect of Respiratory Muscle Training in Multiple Sclerosis

Not Applicable
Recruiting
Conditions
Multiple Sclerosis.
Multiple sclerosis
Registration Number
IRCT20200827048542N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
36
Inclusion Criteria

Definite diagnosed relapsing-remitting MS
Year after diagnosed at least one year
Be able to walk without support at least 10 meters
Not have an relapse at least one month
Taking no intravenous corticosteroid drug

Exclusion Criteria

history of any respiratory disease
have an active pulmonary infection
Contraindicated for aerobic activity (such as orthopedic and muscular problem)
smoker
pregnancy
Participate in another research program

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Maximum Inspiratory Pressure. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Body Box machine.;Maximum Expiratory Pressure. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Body Box machine.
Secondary Outcome Measures
NameTimeMethod
Quality of Life. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: SF-36 questionnaire.;Aerobic capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Six Minute Walk Test (6MWT).;Functional capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Timed Up and Go test (TUG).;Forced Expiratory volume in the first second (FEV1). Timepoint: before intervention and 8 weeks after interventio. Method of measurement: Spirometry.;Forced Expiratory volume in the first second (FEV1)/Forced Vital Capacity (FVC). Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Spirometry.;Fatigue. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Modified Fatigue Impact Scale questionnaire (MFIS).
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