ISRCTN10348278
Active, not recruiting
未知
Studying retinal structure with adaptive optics and function with multifocal electroretinogram
ewcastle upon Tyne Hospitals NHS Foundation Trust0 sites40 target enrollmentNovember 9, 2023
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Inherited retinal disease, late-onset retinal degeneration
- Sponsor
- ewcastle upon Tyne Hospitals NHS Foundation Trust
- Enrollment
- 40
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Control
- •1\.1\. Adult between ages of 18 – 80 years old
- •1\.2\. Capable of performing all of the tests in the study procedures
- •1\.3\. Able to give informed consent to all of the procedures.
- •2\. Late\-onset retinal degeneration
- •2\.1\. Adult between ages of 18 – 80 years old
- •2\.2\. Capable of performing all of the tests in the study procedures
- •2\.3\. Able to give informed consent to all of the procedures
- •2\.4\. Have a confirmed genetic diagnosis of L\-ORD
Exclusion Criteria
- •1\. Healthy control
- •1\.1\. Younger than 18 and older than 80 years old
- •1\.2\. Inability of participant to provide informed consent
- •1\.3\. Withdrawal of consent
- •1\.4\. BCVA of less than 6/12 in either eye
- •1\.5\. Participants with a spherical equivalent of greater than 4 dioptres or astigmatism greater than 2 dioptres
- •1\.6\. Taking any medication that can affect retinal function (e.g. Hydroxychloroquine, Deferasirox, Vigabatrin).
- •1\.7\. Known to have any ocular condition that will affect test results/ability to test:
- •1\.7\.1\. Inherited retinal condition
- •1\.7\.2\. Glaucoma
Outcomes
Primary Outcomes
Not specified
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