A randomised double blind placebo controlled study to evaluate the effectiveness of purified d-Limonene as an agent to relieve the symptoms of indigestion and heartbur

Not Applicable

Completed

• Conditions: Gastrointestinal discomfort (indigestion/heartburn); Digestive System; Gastrointestinal discomfort

• Registration Number: ISRCTN96109983
• Lead Sponsor: WRC Laboratories LP (USA)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2001-06-30
• Study Start: 2007-08-16
• Last Update Posted: 8 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Adults over 18 years of age who have experienced symptoms of indigestion and/or heartburn for at least six months.

Exclusion Criteria

1. Known sensitivity to citrus products or by products
2. Known sensitivity to soy bean oil
3. History of gastrointestinal bleeding or ulcers
4. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief of symptoms as reported subjectively by study participants daily for twenty days. Participants rated their symptom relief on the original questionnaires to day 20.

Secondary Outcome Measures

Name	Time	Method
Continued relief of symptoms after completing 10 capsules. A follow up questionnaire was sent out at the six month time-point for feedback on continued relief of symptoms.